CVA with Alcohol withdrawal related Seizures.



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Team:

Interns-

M Supriya 

Sowmya Kota

Mohitha

Amrutha 

Sanjay


Dr Durga Krishna PGY1

Dr Ajith Kumar PGY2

Dr Laxma Reddy PGY3

Dr Manasa PGY3 

Dr Vijayalaxmi (Ast prof.)


A 48 year old male shopkeeper presented with  

C/o seizures 4 days ago,

C/o altered sensorium from 2 days,

C/o aggressive behaviour with irrelevant speech from 2 days.


Patient was apparently asymptomatic 10 yrs back when he reduced alcohol intake following which he developed seizures- GTCS involving all four limbs with post ictal confusion.

No h/o tongue bite.

Not a/w involuntary micturition or defecation.


H/o similar complaints 1 yr back in February after stopping alcohol for 4 days during his son’s wedding. 


H/o fall while walking 10 days ago.

H/o similar episode 4 days ago after reducing alcohol intake. LOC+ for 15 mins, tonic clonic movements of both upper and lower limbs, uprolling of eyes+, frothing+, post ictal confusion+


PAST HISTORY:

H/o admission in de addiction centre in kims in 2018 for 15 days.

K/c/o pulmonary koch’s 1 yr back. Used medication for 6 months. 

K/c/o epilepsy from 10 yrs and was on medication - Tab.EPTOIN 100mg (1-X-2) for 9 yrs. Stopped medication from 1 year. 

Not a k/c/o HTN, DM, epilepsy, asthma,CVA.


PERSONAL HISTORY:

He is married and he has 2 sons.

He owns a General kirana store.

Reduced appetite.

Mixed diet.

Known chronic alcoholic from 30 yrs.

He used to drink whiskey 90ml/day increased to 720ml/day in 2 years.

 He used to drink Toddy 250ml once a month increased to 2 litres 4 times a week.

H/o tobacco chewing from 25 yrs- 1/2 pack per day increased to 5 packs per day.

Reduced sleep.

Normal bowel and bladder movements.

No known allergies.


O/E-

 Patient is conscious, irritable state at admission

Icterus+


No pallor, cyanosis, clubbing, pedal edema, generalised lymphadenopathy.






Vitals:

Bp- 110/70mmhg

Pr-132bpm

Rr-22cpm

Grbs-114mg%

Spo2-98%


SYSTEMIC EXAMINATION:

CVS- S1S2 +

          No murmurs.

RS- BLAE+ 

        NVBS+

P/A- soft, nontender.

        No organomegaly.

        Bowel sounds+





CNS- 

HIGHER MENTAL FUNCTIONS-are intact


All CRANIAL NERVES are intact

MOTOR SYSTEM
1) Nutrition - normal
2) Tone - Both upper limbs and lower limbs tone normal
3)Power- 5/5 in both upper and lower limbs
4)Reflexes
Superficial reflexes- intact
Deep tendon reflexes

Reflexes.   Right.      Left.  

Biceps     ++            ++

Triceps    ++            ++

Supinator  -               -

Knee       ++             ++

Ankle      ++             ++

Plantar   Flexion     Flexion











SENSORY SYSTEM
Spinothalamic- intact
Dorsal column - intact
Cortical sensations -intact

CEREBRLLAR FUNCTION TEST
Finger nose test-normal
Knee heel test-normal
Dysdiadokokinesia-normal

Psychiatry referral: 






             





INVESTIGATIONS:


            





MRI brain(done outside)- acute infarct in left paraventricular region with lacunar infarcts in b/l paraventricular region 


DIAGNOSIS-

CVA with acute infarct in left paraventricular region with lacunar infarcts in b/l paraventricular region with alcohol withdrawal syndrome.


TREATMENT:

1.Inj.Thiamine 100mg/IV/BD IN 100ml NS.

2.Inj. Optineuron 1 amp in 1 unit NS/ IV/OD.

3.Tab. Eptoin 100mg/PO/BD.

4.Inj.Pantop 40mg/IV/OD.

5.Inj.Lorazepam2cc/IV/SOS.

6.Inj.Aspirin 75mg PO/OD.

7.Inj. Clopidogrel 75mg PO/OD.

8.Tab. Atorvastatin 40mg/PO/OD.

9.Tab. Lorazepam 2mg 2 tablets PO/OD.

10.Inj. Mannitol 100ml IV stat.







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