CVA with Alcohol withdrawal related Seizures.
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Team:
Interns-
M Supriya
Sowmya Kota
Mohitha
Amrutha
Sanjay
Dr Durga Krishna PGY1
Dr Ajith Kumar PGY2
Dr Laxma Reddy PGY3
Dr Manasa PGY3
Dr Vijayalaxmi (Ast prof.)
A 48 year old male shopkeeper presented with
C/o seizures 4 days ago,
C/o altered sensorium from 2 days,
C/o aggressive behaviour with irrelevant speech from 2 days.
Patient was apparently asymptomatic 10 yrs back when he reduced alcohol intake following which he developed seizures- GTCS involving all four limbs with post ictal confusion.
No h/o tongue bite.
Not a/w involuntary micturition or defecation.
H/o similar complaints 1 yr back in February after stopping alcohol for 4 days during his son’s wedding.
H/o fall while walking 10 days ago.
H/o similar episode 4 days ago after reducing alcohol intake. LOC+ for 15 mins, tonic clonic movements of both upper and lower limbs, uprolling of eyes+, frothing+, post ictal confusion+
PAST HISTORY:
H/o admission in de addiction centre in kims in 2018 for 15 days.
K/c/o pulmonary koch’s 1 yr back. Used medication for 6 months.
K/c/o epilepsy from 10 yrs and was on medication - Tab.EPTOIN 100mg (1-X-2) for 9 yrs. Stopped medication from 1 year.
Not a k/c/o HTN, DM, epilepsy, asthma,CVA.
PERSONAL HISTORY:
He is married and he has 2 sons.
He owns a General kirana store.
Reduced appetite.
Mixed diet.
Known chronic alcoholic from 30 yrs.
He used to drink whiskey 90ml/day increased to 720ml/day in 2 years.
He used to drink Toddy 250ml once a month increased to 2 litres 4 times a week.
H/o tobacco chewing from 25 yrs- 1/2 pack per day increased to 5 packs per day.
Reduced sleep.
Normal bowel and bladder movements.
No known allergies.
O/E-
Patient is conscious, irritable state at admission
Icterus+
No pallor, cyanosis, clubbing, pedal edema, generalised lymphadenopathy.
Vitals:
Bp- 110/70mmhg
Pr-132bpm
Rr-22cpm
Grbs-114mg%
Spo2-98%
SYSTEMIC EXAMINATION:
CVS- S1S2 +
No murmurs.
RS- BLAE+
NVBS+
P/A- soft, nontender.
No organomegaly.
Bowel sounds+
CNS-
HIGHER MENTAL FUNCTIONS-are intact
Reflexes. Right. Left.
Biceps ++ ++
Triceps ++ ++
Supinator - -
Knee ++ ++
Ankle ++ ++
Plantar Flexion Flexion
Psychiatry referral:

INVESTIGATIONS:
MRI brain(done outside)- acute infarct in left paraventricular region with lacunar infarcts in b/l paraventricular region
DIAGNOSIS-
CVA with acute infarct in left paraventricular region with lacunar infarcts in b/l paraventricular region with alcohol withdrawal syndrome.
TREATMENT:
1.Inj.Thiamine 100mg/IV/BD IN 100ml NS.
2.Inj. Optineuron 1 amp in 1 unit NS/ IV/OD.
3.Tab. Eptoin 100mg/PO/BD.
4.Inj.Pantop 40mg/IV/OD.
5.Inj.Lorazepam2cc/IV/SOS.
6.Inj.Aspirin 75mg PO/OD.
7.Inj. Clopidogrel 75mg PO/OD.
8.Tab. Atorvastatin 40mg/PO/OD.
9.Tab. Lorazepam 2mg 2 tablets PO/OD.
10.Inj. Mannitol 100ml IV stat.
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